Data and Biosamples are available through two different application processes, see appropriate section below
Jump to: Data Application | Samples Application
If you have already received approval to access ADNI data, you can login to search and download data from the repository. To request approval, see below.
LOGINAll ADNI data are shared without embargo through the LONI Image and Data Archive (IDA), a secure research data repository. Interested scientists may obtain access to ADNI imaging, clinical, genomic, and biomarker data for the purposes of scientific investigation, teaching, or planning clinical research studies. Access is contingent on adherence to the ADNI Data Use Agreement and the publications’ policies outlined in the documents listed below. Note: documents are subject to updates by ADNI.
Data from several dementia studies complementary to ADNI are also available through the IDA. These include the DoD-ADNI study, which measures the effects of traumatic brain injury and post-traumatic stress disorder on Alzheimer’s disease in veterans, and the AIBL study (Australian Imaging Biomarkers and Lifestyle Study of Aging). More information about DoD-ADNI and AIBL may be found on the Collaborative Studies page.
The application process includes acceptance of the Data Use Agreement and submission of an online application form. The application must include the investigator’s institutional affiliation and the proposed uses of the ADNI data. ADNI data may not be used for commercial products or redistributed in any way.
Click on the buttons below to apply for ADNI data, DoD-ADNI data, AIBL data, or all three.
The ADNI Data Sharing and Publications Committee (DPC) generally reviews data use applications within two weeks of submission. Each application is carefully reviewed to verify investigator affiliation with a scientific or educational institution and on the basis of the proposed research or data use. Incomplete applications or those without a clear focus will not receive approval. The results of the Committees review will be sent via email. Approved applicants will receive login information to access and download ADNI data from the LONI Image and Data Archive (IDA).
A provision of the ADNI Data Use Agreement requires submission of an annual update. Accounts will automatically expire if no update is submitted within the allotted time. You will receive an email reminding you that your annual update is due approximately one month before your account expires. You may also add or remove co-investigators, submit manuscripts and update contact information at that time or at any time in advance. Login to update your account information.
If you have questions about using your ADNI data account, please review the User Account Frequently Asked Questions or contact us.
The overall goal of ADNI is to validate biomarkers for AD clinical trials. ADNI is a complex and unique collection of data, imaging and biospecimens gathered longitudinally from carefully phenotyped subjects. It has massive potential for breakthrough discoveries in the field of Alzheimer’s research. The biospecimens serve as a valuable resource for replicating important new findings and validating novel biomarkers. The answer to a disease modifying therapy for AD may be in the existing ADNI database/biosample collection, waiting to be discovered. Any scientist may apply for access to data and samples collected by ADNI. However, ADNI samples are precious and governed accordingly by policies and protocols.
Biospecimens such as genetic material, blood, plasma, serum, urine, brain tissue and cerebrospinal fluid collected from ADNI participants are available through ADNI and managed by the Resource Allocation Review Committee (RARC) or Biospecimen Review Committee (BRC).
Information about ADNI samples available for requests as well as request policies and procedures are below.
Investigators interested in using ADNI biosamples for their scientific study are asked to submit an initial request which will be reviewed for appropriateness. Investigators of approved studies will be invited to a submit an ADNI Biospecimens Full Application.
For more details, click How to Request Samples below.
Questions should be sent to cat.conti@ncire.org.
