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Principal Investigator  
Principal Investigator's Name: AmirHussein Abdolalizadeh
Institution: Student's Scientific Research Center
Department: Interdisciplinary Neuroscience Research Program
Country:
Proposed Analysis: There's a strong genetic background underlying the Alzheimer's Disease and it's associated disabilities, mostly cognitive functions. In the present study we're trying to find the imaging correlations of the genetic biomarkers in both AD and healthy controls to identify genetic risk factors affecting brain function and structure that may predispose a otherwise healthy brain into an Alzheimer's disease malfunctioning brain. In the first step, we will analyze the SNPs of APOE gene and the imaging findings associated with them in healthy population (e.g. using VBM). We're also trying to find the effects of serum biomarkers and genetic factors on the atrophy of the brain using longitudinal VBM in AD patients.
Additional Investigators  
Investigator's Name: Bahram Mohajer
Proposed Analysis: Bahram will do our imaging part using FreeSurfer's longitudinal pipeline.