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Principal Investigator  
Principal Investigator's Name: John Kauwe
Institution: Brigham Young University
Department: Biology
Country:
Proposed Analysis: Aim 1: To measure mitochondrial genome copy number (mtGCN) in the ADNI samples. Aim 2: To examine the associations between mtGCN and Alzheimer’s disease in the ADNI samples. Aim 3: To examine the associations between select genetic variants in the mitochondrial and nuclear genome and mtGCN. ADNI phenotype data will be required to explore the mtGCN phenotype and its relationship to AD, imaging data and CSF biomarkers.
Additional Investigators  
Investigator's Name: Carlos Cruchaga
Proposed Analysis: Assistance in Genetic Analysis