Ongoing Investigations

ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator  
Principal Investigator's Name: Andre Altmann
Institution: University Collage London
Department: Medical Physics and Biomedical Engeneering
Country:
Proposed Analysis: Effect of rare genetic variants on the risk of developing Alzheimer’s disease In this project we plan to analyze the effect of rare genetic variants on the risk of developing Alzheimer’s disease (AD) and the effect on AD-related biomarkers (CSF and neuroimaging). The standard statistical approaches used to analyze SNP data cannot leverage the information on rare variants because they occur only once in the entire dataset. Thus, we will develop graph-based approaches to allow for aggregating information within the same gene or genetic pathway and related these new measures to quantitative phenotypes.
Additional Investigators