Ongoing Investigations

ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator  
Principal Investigator's Name: Pablo Aguiar
Institution: University of Santiago de Compostela
Department: Radiology
Country:
Proposed Analysis: Several neuroimaging tools have been proposed to predict the probability of conversion from MCI (mild cognitive impairment) to AD (Alzheimer's Disease) patients. To date, outstanding results have been obtained from MRI-based volumetry, involving hippocampal volume measurements and medial temporal atrophy, and PET studies, both for hypometabolic areas detection with 18F-FDG PET as measures of amyloid deposits. Current investigations are also focused on new advanced image processing techniques, which can extract large amounts of data from current imaging studies. This has led to the emergence of a new technology based on Big Data techniques, aimed at correlating the image-derived information and clinical data. Our project aims to develop and implement new processing algorithms based on advanced texture analysis and histogram-based methods, which will be applied for the first time in neuroimaging PET/MRI, with the aim of generating large amounts of integrated information. Based on this, our final aim is to develop a new tool to predict the probability of conversion from MCI (mild cognitive impairment) to AD (Alzheimer's Disease) patients.
Additional Investigators