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Principal Investigator  
Principal Investigator's Name: Katherine Houghton
Institution: RTI Health Solutions
Department: Health Economics
Country:
Proposed Analysis: RTI Health Solutions are working in collaboration with Eisai to identify a best-practices cost-effectiveness modeling approach that can be used in patients at different stages of mild cognitive impairment and Alzheimer's disease. The ADNI data will be reviewed to identify the extent to which there is data to estimate credible transition rates and other CE model input parameters for the recommended model structure. Such data will include natural history and biomarker data. If the data can be used for the CE model, RTI Health Solutions will use it within the CE model.
Additional Investigators  
Investigator's Name: Amir Abbas Tahami Monfared
Proposed Analysis: Derive ADCOMS values to delineate the staging of cognitive decline across the predementia and AD continuum
Investigator's Name: Quanwu Zhang
Proposed Analysis: Derive ADCOMS values to delineate the staging of cognitive decline across the predementia and AD continuum
Investigator's Name: Josephine Mauskopf
Proposed Analysis: Derive ADCOMS values to delineate the staging of cognitive decline across the predementia and AD continuum