There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | David Greenstein |
| Institution: | Multimodal Imaging Services Corporation |
| Department: | Engineering |
| Country: | |
| Proposed Analysis: | Diffusion imaging has demonstrated sensitivity to structural brain changes in Alzheimer's disease (AD). However, there remains a need for a more complete characterization of microstructural alterations occurring at the earliest disease stages, and how these changes relate to underlying neuropathology. We propose to evaluate the sensitivity of restriction spectrum imaging (RSI), an advanced diffusion MRI technique, on microstructural changes in pre-clinical AD as well as the advancing stages of AD. |
| Additional Investigators | |
| Investigator's Name: | Renee George |
| Proposed Analysis: | Analysis Diffusion imaging has demonstrated sensitivity to structural brain changes in Alzheimer's disease (AD). However, there remains a need for a more complete characterization of microstructural alterations occurring at the earliest disease stages, and how these changes relate to underlying neuropathology. We propose to evaluate the sensitivity of restriction spectrum imaging (RSI), an advanced diffusion MRI technique, on microstructural changes in pre-clinical AD as well as the advancing stages of AD. UPDATED (2019-04-26) :There are no changes to the proposed analysis from last year. No manuscripts to report as of yet however, we plan on submitting an abstract within a few months. |
| Investigator's Name: | Christine Swisher |
| Proposed Analysis: | Analysis Diffusion imaging has demonstrated sensitivity to structural brain changes in Alzheimer's disease (AD). However, there remains a need for a more complete characterization of microstructural alterations occurring at the earliest disease stages, and how these changes relate to underlying neuropathology. We propose to evaluate the sensitivity of restriction spectrum imaging (RSI), an advanced diffusion MRI technique, on microstructural changes in pre-clinical AD as well as the advancing stages of AD. UPDATED (2019-04-26) :There are no changes to the proposed analysis from last year. No manuscripts to report as of yet however, we plan on submitting an abstract within a few months. |
