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Principal Investigator  
Principal Investigator's Name: Andrea Avena-Koenigsberger
Institution: Indiana University
Department: Psychological and Brain Sciences
Proposed Analysis: Our aim is to study the spread and accumulation of tau and amyloid-beta, by using a variety of diffusion-based models implemented on networks of anatomical connections (obtained from diffusion weighted imaging). Building on previous work by Raj et al. (2012, 2015), we will test a family of parametrized diffusion operators as possible mechanisms driving the spread and effects of disease factors known to be related with the onset of AD.
Additional Investigators