There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | John Farrell |
Institution: | Boston University Medical School |
Department: | Biomedical Genetics |
Country: | |
Proposed Analysis: | The overall goal of this project is to delineate the complete genetic architecture of Alzheimer disease (AD). We plan apply various analytical methods to detect AD- related genes or other functional elements that harbor rare variants using the ADSP, ADNI and other AD cohort sequence data. We will use various pipelines to identify structural variants . A particular interest will be identifying LOF variants in known AD genes. We will also develop an imputation reference panel from the AD cohorts to impute into larger GWAS such as the ADGC and UK Biobank GWAS data sets. |
Additional Investigators |