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Principal Investigator  
Principal Investigator's Name: Zhengjia Dai
Institution: Sun Yat-sen University
Department: Psychology
Country:
Proposed Analysis: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that impairs patients’ cognitive function and behaviors. There were many studies about AD in both functional connectivity and structural connectivity, which have found that AD had significant abnormal connections compared with healthy controls (HC). But for the AD diagnosis, there still have no certain answers. We want to use machine learning methods, to do the classification for both functional connectivity and structural connectivity in AD, MCI and HC. We want to use the big data to find whether there is a kind of model could predict AD from HC. Further, we want to test whether the model is also suit for predict MCI from HC. If so, these large weighted features might be the core impact factor in AD. Thus, we apply for ADNI datasets.
Additional Investigators  
Investigator's Name: Ying Lin
Proposed Analysis: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that impairs patients’ cognitive function and behaviors. There were many studies about AD in both functional connectivity and structural connectivity, which have found that AD had significant abnormal connections compared with healthy controls (HC). But for the AD diagnosis, there still have no certain answers. We want to use machine learning methods, to do the classification for both functional connectivity and structural connectivity in AD, MCI and HC. We want to use the big data to find whether there is a kind of model could predict AD from HC. Further, we want to test whether the model is also suit for predict MCI from HC. If so, these large weighted features might be the core impact factor in AD. Thus, we apply for ADNI datasets.
Investigator's Name: Yue Gu
Proposed Analysis: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that impairs patients’ cognitive function and behaviors. There were many studies about AD in both functional connectivity and structural connectivity, which have found that AD had significant abnormal connections compared with healthy controls (HC). But for the AD diagnosis, there still have no certain answers. We want to use machine learning methods, to do the classification for both functional connectivity and structural connectivity in AD, MCI and HC. We want to use the big data to find whether there is a kind of model could predict AD from HC. Further, we want to test whether the model is also suit for predict MCI from HC. If so, these large weighted features might be the core impact factor in AD. Thus, we apply for ADNI datasets.
Investigator's Name: Junji Ma
Proposed Analysis: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that impairs patients’ cognitive function and behaviors. There were many studies about AD in both functional connectivity and structural connectivity, which have found that AD had significant abnormal connections compared with healthy controls (HC). But for the AD diagnosis, there still have no certain answers. We want to use machine learning methods, to do the classification for both functional connectivity and structural connectivity in AD, MCI and HC. We want to use the big data to find whether there is a kind of model could predict AD from HC. Further, we want to test whether the model is also suit for predict MCI from HC. If so, these large weighted features might be the core impact factor in AD. Thus, we apply for ADNI datasets.
Investigator's Name: Xitian Chen
Proposed Analysis: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that impairs patients’ cognitive function and behaviors. There were many studies about AD in both functional connectivity and structural connectivity, which have found that AD had significant abnormal connections compared with healthy controls (HC). But for the AD diagnosis, there still have no certain answers. We want to use machine learning methods, to do the classification for both functional connectivity and structural connectivity in AD, MCI and HC. We want to use the big data to find whether there is a kind of model could predict AD from HC. Further, we want to test whether the model is also suit for predict MCI from HC. If so, these large weighted features might be the core impact factor in AD. Thus, we apply for ADNI datasets.