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Principal Investigator  
Principal Investigator's Name: Shu Jiang
Institution: Washington university in st.louis
Department: surgery
Country:
Proposed Analysis: We are interested in doing dynamic prediction to the progression of AD with multiple baseline and time-varying proteins in the brain. We plan to adopt machine learning algorithms along with functional data analysis in conducting the prediction. In particular, we will assess the proposed model discrimination and calibration performance and disseminate results in a statistical paper.
Additional Investigators  
Investigator's Name: Yijun Xie
Proposed Analysis: Collaborator on this project
Investigator's Name: Graham Colditz
Proposed Analysis: Collaborator on the proposed project
Investigator's Name: Shawn Wenren
Proposed Analysis: Image analysis on the FMRI data
Investigator's Name: Haolun Shi
Proposed Analysis: Dynamic risk prediction with time-varying cognition scores