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Principal Investigator  
Principal Investigator's Name: Erin Bennett
Institution: The George Washington University Milken Institute School of Public Health
Department: Epidemiology
Country:
Proposed Analysis: To investigate whether findings from ADNI generalize more broadly to other populations, we are comparing associations estimated in ADNI to those estimated in the Atherosclerosis Risk in Communities (ARIC) study, which initially recruited participants randomly from four US communities. Data from ADNI and ARIC are pooled to estimate associations between risk factors and cognitive or imaging data, and between cognitive and imaging data, using adjusted linear and logistic regression models. Models include a term for cohort and its interaction with the variable of interest, allowing for cohort-specific estimates and statistical evaluation of cohort differences.
Additional Investigators