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Principal Investigator  
Principal Investigator's Name: Yulan Dong
Institution: the First Affiliated Hospital of University of South China
Department: Department of Radiology
Country:
Proposed Analysis: The clinical study of cognitive (decline) and depression related neuroimaging markers in Alzheimer's disease(AD) patients. This study will collect AD patients and volunteers. For all subjects complete various clinical assessments and general information. Analysis of structural phase and function phase. Use other software in Matlab for statistical calculations and display of image results. Finally, deep study on substructure of brain parenchyma, to expound the neural network-specific changes in the occurrence of cognitive impairment or depression in patients with diabetes mellitus to achieve predictive effects. It could provide evidence for the early recognition and intervention of diabetic complications.
Additional Investigators  
Investigator's Name: Hao Lei
Proposed Analysis: In this study, functional magnetic resonance imaging and perfusion imaging in patients with Alzheimer's disease were analyzed. To explore the connection of brain regions related to speech function and quantitatively extract physiological parameters in patients with AD, and to reveal the relationship and change law between AD and cerebral blood flow network, in order to find biomarkers that determine the recovery of speech ability in AD.