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Principal Investigator  
Principal Investigator's Name: Paul Adlard
Institution: The Florey Institute for Neuroscience and Mental Health
Department: Neurodegeneration
Proposed Analysis: A number of investigations centred around the role of metals, zinc in particular, in both normal and pathological cognitive decline will be undertaken. These will include SNP analysis of targets such as the zinc transporter 3 gene, and how these may predict the onset of cognitive decline and/or structural alterations in the brain that are indicative of the onset or progression of functional decline. We will also study this with the perspective of the downstream role of zinc at the synapse, and how it may have specific interactions with targets such as BDNF, NMDA etc.
Additional Investigators