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Principal Investigator  
Principal Investigator's Name: Anita DeStefano
Institution: Boston University
Department: Biostatistics
Country:
Proposed Analysis: We proposed to perform association analysis to identify genes/variants associated with Alzheimer disease and related traits. We will analyze the ADNI data as part of the Alzheimer Disease Sequencing Project data. The ADNI data will be analyzed separately, and combined with other datasets via meta analysis as well as explore combined association analyses across data sets. Association analyses will include single variant as well as aggregate tests.
Additional Investigators  
Investigator's Name: Josee Dupuis
Proposed Analysis: We will use the ADNI data to perform association analyses for Alzheimer disease and related traits. The ADNI data will be analyzed as part of the Alzheimer Disease Sequencing Project data. Analyses will be performed separately on the ADNI data and combined with other studies via meta analysis. We will also explore conducting association analyses across studies. Association analysis will include single variant analyses and aggregate tests.
Investigator's Name: Gina Peloso
Proposed Analysis: We will use the ADNI data to perform association analyses for Alzheimer disease and related traits. The ADNI data will be analyzed as part of the Alzheimer Disease Sequencing Project data. Analyses will be performed separately on the ADNI data and combined with other studies via meta analysis. We will also explore conducting association analyses across studies. Association analysis will include single variant analyses and aggregate tests.
Investigator's Name: Achilleas Pitsillides
Proposed Analysis: WE PROPOSED TO PERFORM ASSOCIATION ANALYSIS TO IDENTIFY GENES/VARIANTS ASSOCIATED WITH A DISEASE AND RELATED TRAITS. WE WILL ANALYZE THE ADNI DATA AS PART OF THE ALZHEIMER DISEASE SEQUENCING PROJECT DATA. THE ADNI DATA WILL BE ANALYZED SEPARATELY, AND COMBINED WITH OTHER DATASETS VIA META ANALYSIS AS WELL AS EXPLORE COMBINED ASSOCIATION ANALYSES ACROSS DATA SETS ASSOCIATION ANALYSES WILL INCLUDE SINGLE VARIANT AS WELL AS AGGREGATE TESTS.
Investigator's Name: Seung Hoan Choi
Proposed Analysis: We are in the process of conducting single variant and aggregate association analyses in the current WGS release of the ADSP data set that includes ADNI accounting for local and global ancestry. We are examining the occurrence of variants that are clinically relevant for familial Alzheimer Disease in the ADSP WES and ADSP WGS data set that includes ADNI.
Investigator's Name: Nancy Heard-Costa
Proposed Analysis: We are in the process of conducting single variant and aggregate association analyses in the current WGS release of the ADSP data set that includes ADNI accounting for local and global ancestry. We are examining the occurrence of variants that are clinically relevant for familial Alzheimer Disease in the ADSP WES and ADSP WGS data set that includes ADNI.
Investigator's Name: Andy Rampersaud
Proposed Analysis: We will use the ADNI data to perform association analyses for Alzheimer disease and related traits. The ADNI data will be analyzed as part of the Alzheimer Disease Sequencing Project data. Analyses will be performed separately on the ADNI data and combined with other studies via meta analysis. We will also explore conducting association analyses across studies. Association analysis will include single variant analyses and aggregate tests and will account for global and local ancestry.