• Select the area you would like to search.
  • ACTIVE INVESTIGATIONS Search for current projects using the investigator's name, institution, or keywords.
  • EXPERTS KNOWLEDGE BASE Enter keywords to search a list of questions and answers received and processed by the ADNI team.
  • ADNI PDFS Search any ADNI publication pdf by author, keyword, or PMID. Use an asterisk only to view all pdfs.
Principal Investigator  
Principal Investigator's Name: Vivian Chu
Institution: Queens College, CUNY
Department: Psychology
Proposed Analysis: The objective of this proposal is to investigate the relationship between a seminal cognitive marker derived from the Serial Position Effect (SPE) and a critical early biomarker, phosphorylated tau in cerebrospinal fluid (CSF P-tau), and to determine whether combining both metrics will improve detection of high-risk individuals in preclinical AD and prediction of disease progression. Itemized list-learning data from the RAVLT that will be used to calculate SPE metrics. To test the hypothesis that primacy performance predicts CSF P-tau concentrations, a linear regression analysis will be conducted. The main predictor is the ratio of primacy items recalled in the learning, and short and long delay trials. The outcome variable is baseline CSF P-tau levels. Three Cox Regression hazards models will be run on the HC participants to compare their prognostic performance concerning HC-to-AD conversion.
Additional Investigators