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Principal Investigator  
Principal Investigator's Name: Marta Barrachina
Institution: ADmit Therapeutics SL
Department: R&D
Proposed Analysis: We are seeking for DNA from whole blood samples (or blood samples) from MCI patients with CDR=0.5 collected in the baseline visit. It is necessary that these patients show a clinical follow-up higher than 36 months to know if they are MCI patients progressed to AD or remain as MCI. This study is focused in determining the mtDNA methylation profile among MCI patients progressed to AD with respect to MCI patients non-progressed to AD. In parallel, we want to monitor our biomarkers (mtDNA methylation) along disease progression. Therefore, we are also interested in getting access to three time point collections from the same subject: DNA samples from the times points CDR=0 (control), CDR=0,5 (MCI) and CDR=>1 (AD). We submitted the Full Proposal at February 28th. We need to know clinical information about DNA samples available.
Additional Investigators