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Principal Investigator  
Principal Investigator's Name: Anshuman Swain
Institution: University of Pennsylvania
Department: Department of Radiology
Proposed Analysis: I am a current PhD student under my advisor Ravinder Reddy. I am currently working on metabolic alterations and structural biomarkers of AD pathology. Specifically, I am working on developing sequences for improved myelin detection. I have recently started working on deep learning methodologies and I am very interested in anomaly detection. To my understanding, DWI has been used for observing physiological changes in Alzheimer's disease, especially in white matter tracts. I would like to train a neural network for anomaly detection in white matter tracts of mild to severe AD using DWI (and potentially other contrasts) as this contrast shows sensitivity to myelination in the brain.
Additional Investigators