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Principal Investigator  
Principal Investigator's Name: Antoine Soubret
Institution: F. Hoffmann-La Roche Ltd
Department: Roche Pharma Research and Early Development (pRED)
Proposed Analysis: We would like to study the performance of mathematical models, built with the ADNI dataset, to describe disease progression (e.g. https://doi.org/10.1002/psp4.12974, https://doi.org/10.1002/sim.8932), as well as biomarker time profiles (e.g. https://doi.org/10.1002/alz.12363). The aim will be to leverage these models to support the analysis of clinical trials by combining short-term study data with long term model predictions.
Additional Investigators