ADNI1
Participant Pool:
- 200 Normal Controls
- 400 MCI
- 200 Mild AD
Objectives:
- Develop improved methods that create uniform standards for acquiring longitudinal, multi-site MRI and PET data on patients with Alzheimer’s disease (AD), mild cognitive impairment (MCI), and elderly controls.
- Acquire a generally accessible data repository which describes longitudinal changes in brain structure and metabolism as well as clinical/cognitive and biomarker data for the validation of imaging surrogates.
- Develop methods which will provide maximum power to determine treatment effects in trials involving these patients.
- Test a series of hypotheses based on the clinical and biomarker data.