There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Sungmin Hong |
| Institution: | Massachusetts General Hospital |
| Department: | Neurology |
| Country: | |
| Proposed Analysis: | We aim to anaylze the relationship between the anatomical shapes of subcortical structures, more specifically striatal complex, and cognitive decline. The first step of a pipeline is the segmentation of striatal complexes using FreeSurfer-based methods and deep-learning based methodologies. After the segmentation, the anatomical shapes of the striatal complexes will be represented as medial representations on the Riemannian manifold. We aim to develop a new methodology on modeling flexible and longitudinal shape changes that can take into account multiple explanatory variables for manifold-valued shape data. The implemented framework will be applied to the stroke-related research with clinical-grade images. |
| Additional Investigators |
