Alzheimer’s Disease Neuroimaging Initiative

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Clinical Assessments

Clinical Assessments

ADNI collects a number of cognitive assessments and questionnaires for in-clinic participants. These have changed over time, please see the table below for list of assessments and availability across phases.

Additionally, participants receive a physical exam (i.e. vital signs, comprehensive physical, etc.) and a neurological exam at every in-clinic visit.

In-clinic participants are required to have a study partner. The study partner also answers a limited number of questionnaires about the participant, see table below.

In-clinic Participants' Questionnaires

Participant Assessments/Questionnaires by Name	ADNI1 start 2005	ADNI-GO start 2010	ADNI2 start 2011	ADNI3 start 2016	ADNI4 2023
Abbreviated Multidimensional Acculturation Scale (AMAS; for Latinx participants only)					X
Alzheimer’s Disease Assessment Scale-Cog13 (w/ delayed recall and number cancellation; ADAS-Cog)	X	X	X	X	X
American National Adult Reading Test (AMNART)				X	X
Boston Naming Test	X	X	X
Category Fluency (Animals)	X	X	X	X	X
Category Fluency (Vegetables)	X
Clinical Dementia Rating scale (CDR)	X	X	X	X	X
Clock Drawing	X	X	X	X	X
Cognitive Change Index (CCI)			X	X
Cogstate Brief Battery (CBB)			X	X
Digit span (forward/backward; collected under MOCA after ADNI1)	X
Digit symbol substitution (collected under MOCA after ADNI1)	X
Everyday Cognition 39-item (ECog)		X	X	X
Everyday Cognition 12-item (ECog 12-item) collected in-clinic					X
Everyday Cognition 12-item (ECog 12-item) collected remotely (ADNI online, remote longitudinal monitoring)					X
Financial Capacity Instrument short form (FCI)				X
Geriatric Depression Scale (GDS)	X	X	X	X	X
Hollingshead Index					X
Impact of Events (for amyloid PET disclosure only)					X
Logical Memory I and II	X	X	X	X	X
Mini Mental State Examination (MMSE)	X	X	X	X	X
Modified Hachinski Ischemic Score	X	X	X	X
Montreal Cognitive Assessment (MoCA)		X	X	X	X
Multi-Lingual Naming Test (MINT)				X	X
Novoic Storyteller collected remotely (ADNI online, remote longitudinal monitoring)					X
Brief Perceived Ethnic Discrimination Questionnaire - Community Version (PEDQ-CV)					X
Perceived Stress Scale (PSS)					X
Rey Auditory Verbal Learning Test (AVLT)	X	X	X	X	X
Rural Urban Commuting Area (RUCA)					X
Rural Urban Continuum Code (RUCC)					X
Ryff Purpose of Life (for amyloid PET disclosure only)					X
Trails A & B	X	X	X	X	X
Word Accentuation Test - Chicago (WAT; for Spanish-language participants in place of AMNART)					X

Study Partner/ Informant Questionnaires

Study Partner/Informant Questionnaires and Assessments by Name	ADNI1 start 2005	ADNI-GO start 2010	ADNI2 start 2011	ADNI3 start 2016	ADNI4 2023
Activities of Daily Living (FAQ)	X	X	X	X	X
Clinical Dementia Rating (CDR)	X	X	X	X	X
Cognitive Change Index (CCI)			X	X
Everyday Cognition 39-item (ECog)		X	X	X
Everyday Cognition 12-item (ECog 12-item) collected in-clinic					X
Everyday Cognition 12-item (ECog 12-item) collected remotely (ADNI online, remote longitudinal monitoring)					X
Neuropsychiatric Inventory (NPI)			X	X	X
Neuropsychiatric Inventory (NPI-Q)	X	X	X	X	X