Alzheimer’s Disease Neuroimaging Initiative

Data and Samples
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ADNI Samples
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Biospecimen Collections

Biospecimen Collections

Note that there may exist some samples that were collected which do not have associated data. There are analyses that may not be completed, but we have material that has the potential to be used.

Biospecimen Collections over ADNI Phases

Sample Type	ADNI1 start 2005	ADNI-GO start 2010	ADNI2 start 2011	ADNI3 start 2016	ADNI4 2023
Genomic DNA	X	X	X	X
Cell Line DNA	X	X	X	X
Lymphoblastoid Cell Lines	X	X	X	X
PBMC (for iPSC)			X	X	X
iPSC lines				X
RNA (Paxgene)		X	X	X	X
RBC				X
Whole Blood (for Genomic DNA) - Remote Blood Cohort					X
Plasma - In-Clinic Cohort	X	X	X	X	X
Plasma - Remote Blood Cohort					X
Serum	X	X	X	X	X
CSF	X	X	X	X	X
Urine	X
Brain tissue* - Formalin-fixed paraffin-embedded (FFPE)	X	X	X	X	X
Brain tissue* - Frozen				X	X
Brain tissue* - Wet fixed	X	X	X	X	X

*Neuropathology is ongoing and date of collection is not dependent on phase but on when people consent to autopsy and specimens are collected. ’X’ Refers to date of participant expiration. Availability varies from case to case.