Question

Question Posted 09/08/14:
Dear ADNI Genetics Core staff,
I am downloading ADNI WGS data for analysis. However, I couldn't find an excel-like file for demographic information. Therefore, I checked WGS_Omni25_BIN_wo_ConsentsIssues.fam file, and I wonder whether the 1st column is ID# and the 5th column is disease phenotype (1-control, 2-AD)?

Thank you so much for your help.

Fan
Response posted 09/08/14 by Sungeun Kim:
Currently, case-control status in column 6 is marked as missing (-9) and you can update it by using diagnosis at a certain visit of your interest. Also, genetic data is using PTID as a subjects in the second column. Because other demographic and phenotypic data files at the LONI are using RID, you can map PTID to RID by looking at "ROSTER.csv".
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Due to serious data quality concerns, all data with PTIDs containing the format 381_S_10### have been removed from the ADNI data repository. ADNI leadership strongly advises that data with these PTIDs not be used in any data analysis, submission of abstracts, or publications. Furthermore, ADNI leadership requests that any abstracts or papers which have been submitted using this data be appropriately revised due to concerns with data quality. More information click here.

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