Question

Question Posted 11/17/16:
Dear Experts. I've collect PET images across ADNI1/ADNIGO/ADNI2 with preprocessing step 3 and with all types of tracers (FDG, AV45, PIB, etc.). I'd like to tell which tracer was implemented in a specific image, and I can only find it within the "Description" column in the csv file downloaded from Image Collection page. For example: "AV45 Coreg, Avg, Standardized Image and Voxel Size <- ADNI Brain PET: Raw AV45".

By extracting the first character in the string, four types of character can be found: "AV1451", "AV45", "AV45-Early", "", "PIB".

where I infer "" to be image implemented by FDG.

My question is:
1. What does "AV45-Early" means ? Is it the same as "AV45" ?
2. Is there any better way to identify the type of tracer ?

thanks

Philip Lin
PhD student
Response posted 11/17/16 by Robert Koeppe:
The "Early AV-45" scans are acquired from 0-20 min post-injection. The processed images are merely a sum of some of the "early" frames and more closely represent blood flow than amyloid. It is the same tracer (AV45), but not at a time where one can measure amyloid deposition.
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Due to serious data quality concerns, all data with PTIDs containing the format 381_S_10### have been removed from the ADNI data repository. ADNI leadership strongly advises that data with these PTIDs not be used in any data analysis, submission of abstracts, or publications. Furthermore, ADNI leadership requests that any abstracts or papers which have been submitted using this data be appropriately revised due to concerns with data quality. More information click here.

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