There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | John Absher |
| Institution: | University of South Carolina Greenville |
| Department: | Neurology |
| Country: | |
| Proposed Analysis: | If possible, I would like to examine clinical data to identify subjects with AD who have a history of traumatic brain injury (TBI), compare sMRI from the AD subjects with TBI to those without TBI, and look for exosomes (in serum) and neuroanatomical profiles/patterns that may distinguish these two groups. I hypothesize that AD subjects with and without TBI will have similar patterns of regional cortical thinning, and overlapping exosomal markers, but additional exosomal markers in the AD+TBI group may help explain why TBI increases risk for a broad spectrum of neurodegenerative diseases. |
| Additional Investigators | |
| Investigator's Name: | Terri Bruce |
| Proposed Analysis: | Analyze fluid biomarkers identified by other team members to determine how these may be identified using human exosomes obtained from individuals with TBI to assess the risk of neurodegenerative diseases. |
| Investigator's Name: | Derek Andrew Brown |
| Proposed Analysis: | Dr. Brown will assist with the statistical analysis of the ADNI data related to the TBI study. |
| Investigator's Name: | Booyong Hur |
| Proposed Analysis: | Booyong is Dr. Brown's postdoctoral student who is collaborating on the statistical analysis of the ADNI/TBI data. |
| Investigator's Name: | Samantha Kanny |
| Proposed Analysis: | Samanatha will work with Dr. Brown to perform the statistical analysis of the datasets. Specifically, we are considering network or graph theory approaches to analyzing data across sites, because the effects of TBI may differ considerably among patients. Separate anatomical sites of damage may explain the difficulty prior investigators have had identifying differences between TBI and non-TBI subjects. |
| Investigator's Name: | Jonathan Wade |
| Proposed Analysis: | Mr. Wade is assisting with the clinical analysis of TBI subjects in comparison to non-TBI subjects. |
| Investigator's Name: | Madisen Faulkner |
| Proposed Analysis: | Madisen is a medical student who will help supervise undergraduate students in analyzing and interpreting clinical, demographic and imaging variables that distinguish TBI from non-TBI subjects. |
| Investigator's Name: | Paige Novota |
| Proposed Analysis: | Paige will assist other students and work with the team to analyze and interpret data differentiating TBI and non-TBI subjects. |
| Investigator's Name: | Kshiraj Talati |
| Proposed Analysis: | Kshiraj is a high school student gaining exposure to neuroimaging research by participating in the ADNITBI study with a team of other investigators. He will help with image data pre-processing and other assigned tasks. |
| Investigator's Name: | Katherine Hough |
| Proposed Analysis: | Katherine is a student investigator assisting with the ADNITBI study. |
| Investigator's Name: | Megan Hubbard |
| Proposed Analysis: | Megan is a student investigator assisting with the ADNITBI study. |
| Investigator's Name: | Vanessa Martinez |
| Proposed Analysis: | Vanessa is a student research assistant participating in the ADNITBI study. |
| Investigator's Name: | Abby Mazzollini |
| Proposed Analysis: | Abby is a student investigator in the ADNITBI study. |
| Investigator's Name: | Mudra Patel |
| Proposed Analysis: | Mudra is a student investigator in the ADNITBI study. |
| Investigator's Name: | Savannah Patterson |
| Proposed Analysis: | Savannah is a student investigator working on the ADNITBI study. |
| Investigator's Name: | Rebekah Rocha |
| Proposed Analysis: | Rebekah is a student investigator in the ADNITBI study. |
| Investigator's Name: | Amy Watson |
| Proposed Analysis: | Amy is a student investigator in the ADNITBI study. |
| Investigator's Name: | Braelyn Webb |
| Proposed Analysis: | Braelyn is a student investigator in the ADNITBI study. |
| Investigator's Name: | Emily Broderick |
| Proposed Analysis: | Emily is a student investigator in the ADNITBI study. |
| Investigator's Name: | Christian Creighton |
| Proposed Analysis: | Christian is a medical student investigator involved in the ADNITBI study. |
| Investigator's Name: | Cecilia Cancellaro |
| Proposed Analysis: | Cecilia is a high school research participant in the ADNITBI study. |
