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Principal Investigator  
Principal Investigator's Name: Adrian Heeger
Institution: University Hospital Düsseldorf, Germany
Department: Department of Radiology
Proposed Analysis: Estimating regional deviations of brain volume from a patient’s normative age cohort is challenging and entails immense inter-reader variation. Concerning this issue, Julian Caspers, a leading member of the Department of Radiology of the University Hospital Düsseldorf, developed an automated software-tool to quantify brain volume and (regional) atrophy in MRI scans. In the current study, we aim to validate this tool and to show possible benefits for radiologists in quantifying brain atrophy. To check for technical accuracy and stability and further demonstrate benefits for clinicians, a test-sample is needed. The ADNI sample, with MRI scans of Alzheimer-Patients, MCI-Patients and a control group provides a perfect test-sample for evaluating an automated brain-atrophy calculation. The data-set will be used on our servers exclusively.
Additional Investigators