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Principal Investigator  
Principal Investigator's Name: Alex Whittington
Institution: Invicro Ltd
Department: Image Analysis
Proposed Analysis: TauIQ: We wish to extend the AmyloidIQ methodology previously published to Tau scans. Briefly the IQ algorithm models a spatially normalised PET scan as the linear combination of two canonical images for non-specific binding and specific signal. With amyloid we found increased power when compared to currently used SUVR methods.
Additional Investigators  
Investigator's Name: Lily Porat
Proposed Analysis: Investigation of the temporal relationship between Amyloid and Tau accumulation in AD. Specifically, finding the lag in the stereotypical nonlinear sigmoidal biomarker accumulation curves.