There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Vitaly Dobromyslin |
Institution: | University of Massachussetts, Lowell |
Department: | Biomedical Engineering |
Country: | |
Proposed Analysis: | Alzheimer disease (AD) diagnosis currently requires extensive neuropsychological assessment and brain imaging to confirm concordance of cognitive performance deficits with the characteristic neuroimaging biomarkers of AD. This approach is cost prohibitive and does not scale well to the aging population in resource-limited communities lacking access to the MRI machines required for neuroimaging. Gene expression and proteomics data collected from a blood sample provides a more readily accessible source of diagnostic information, which could aid in AD diagnosis. We propose to look for biomarkers in the gene expression and proteomics data co-varying with the cognitive performance levels and neuroimaging biomarkers, associated with progression to AD. |
Additional Investigators |