There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Haiyuan Yu |
Institution: | Cornell University |
Department: | Computational Biology |
Country: | |
Proposed Analysis: | The analysis aims at developing a new method to detect rare non-coding variants in enhancers in Alzheimer's disease. Briefly, we limit variants discovery within potential enhancer hotspots from a combination of chromatin marks and eRNAs. We will study the effects of newly discovered non-coding variants using mutations from the whole-genome sequencing data, and examine their associations with phenotypes. The requested datasets will be used to establish and validate our method. |
Additional Investigators | |
Investigator's Name: | Yingying Zhang |
Proposed Analysis: | The analysis aims at developing a new method to detect rare non-coding variants in enhancers in Alzheimer's disease. Briefly, we limit variants discovery within potential enhancer hotspots from a combination of chromatin marks and eRNAs. We will study the effects of newly discovered non-coding variants using mutations from the whole-genome sequencing data, and examine their associations with phenotypes. The requested datasets will be used to establish and validate our method. |
Investigator's Name: | You Chen |
Proposed Analysis: | The analysis aims at developing a new method to detect rare non-coding variants in enhancers in Alzheimer's disease. Briefly, we limit variants discovery within potential enhancer hotspots from a combination of chromatin marks and eRNAs. We will study the effects of newly discovered non-coding variants using mutations from the whole-genome sequencing data, and examine their associations with phenotypes. The requested datasets will be used to establish and validate our method. |