There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Caroline Bouter |
| Institution: | UMG Goettingen |
| Department: | Nuclear Medicine |
| Country: | |
| Proposed Analysis: | To whom it may concern, I am a nuclear medicine specialist from the University Medical Center Göttingen, Germany. My research interest is focused on PET-imaging in dementia. Therefore, I would like to work with your database mainly using Amyloid- and FDG-PET data. I would like to analyze FDG-PETs from dementia patients that were scanned in our institution including quantification and compare our data to your dementia collective. We would like to use a machine-based learning approach in order to automatically identify FDG-PET patterns in different forms of dementia using an automated scoring system in order to improve the differentiation between different forms of dementia. Furthermore, we would like to compare our cohort of Lewy body dementia patients with AD patients from your database. We want to use a quantitative approach using cingulate cortex ratios in order to improve the diagnostic value of FDG-PET in the diagnosis of Lewy body dementia. Please do not hesitate to contact me for further details, if needed. Best, Caroline Bouter. |
| Additional Investigators | |
| Investigator's Name: | Yvonne Bouter |
| Proposed Analysis: | My research interest is focused on preclinical studies of dementia as well as brain PET-imaging. Therefore, I would like to work with your database mainly using Amyloid- and FDG-PET data as already propsed by the principle investigator, Caroline Bouter. Best, Yvonne Bouter. |
| Investigator's Name: | Jannis Wenzel |
| Proposed Analysis: | We want to evaluate a possible link between the most common diseases in internal medicine and cognitive performance and amyloid load. Therefore, we want to scan the patient's medical history as well as the medication for several common diseases including hypertonia, myocardial dysfunctions, myocardial infarction, diabetes, adiposity, lipidemia, and thyroid diseases, and evaluate whether the prevalence of these diseases might influence cognitive function, amyloid load or FDG uptake in AD, MCI, SDC, and CN ADNI participants. |
| Investigator's Name: | Robert Max Glasnek |
| Proposed Analysis: | We want to investigate whether inflammatory markers in CSF correlate with cognition, PET biomarkers FBP, and FDG. Furthermore, we would like to evaluate whether the prevalence of inflammatory diseases or the use of anti-inflammatory medication (e.g. prednisolone) influence cognition or biomarkers. |
