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Principal Investigator  
Principal Investigator's Name: Marcela Cespedes
Institution: CSIRO
Department: Australian eHealth Research Centre
Proposed Analysis: Propose to apply recently developed methodology to identify cognitive accelerators and non-accelerators in ADNI study data. This data driven approach uses cognitive trajectories mapped onto a sigmoid curve to identify cognitive accelerators and non-accelerators. Methodology has been previously applied to AIBL study data and presented at CTAD 2021 (poster presentation abstract available https://www.ctad-alzheimer.com/files/files/CTAD21%20Posters.pdf). Intention of this project is to validate methodology with ADNI study data.
Additional Investigators  
Investigator's Name: James Doecke
Proposed Analysis: To validate sigmoid methodology applied to composite cognitive score data, using ADNI study data.