There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Birsu Bac |
| Institution: | Northwestern University |
| Department: | Neuroscience |
| Country: | |
| Proposed Analysis: | I am a Neurobiology Masters student at Northwestern University, investigating AD biomarkers in transgenic rat models for my graduate thesis. At Northwestern, I am working in Dr. John Disterhoft's lab and working in close collaboration with Dr. Robert Vassar and Dr. Jeffrey Savas. My thesis is focused on biomarkers in Alzheimer's Disease and aging in transgenic rat models. While I am mainly conducting immunoassays and mass spectrometry on rat brain samples to research biomarkers, I am interested in comparing my data to those obtained from actual AD patients. My main biomarkers of interest are APOE, Ab1-38/Ab1-40/Ab1-42, phospho-tau, and neuroinflammatory markers such as GFAP, TREM2 and CD44. With ADNI datasets from AD patients, I am hoping to compare my biomarker results from transgenic rat brain tissue with those from human AD patients for further biomarker analysis and validation. The purpose for this request of access is intended for my graduate thesis and research on AD biomarkers and aging. |
| Additional Investigators | |
| Investigator's Name: | John Disterhoft |
| Proposed Analysis: | Dr. Disterhoft is the principal investigator of my lab. While only I will be doing the data analysis, I will be reporting my findings to him to discuss my masters thesis with him. |
| Investigator's Name: | Matt Oh |
| Proposed Analysis: | Dr. Oh is a research professor in my lab whom I work closely with for my graduate studies. While only I will be doing the data analysis, I will be reporting my findings to him to discuss my masters thesis with him. |
