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Principal Investigator  
Principal Investigator's Name: Priyanka Baloni
Institution: Institute for Systems Biology
Department: Hood-Price lab of Systems Biomedicine
Proposed Analysis: Integrating the genetics, clinical and imaging data from ADNI with the genome-scale metabolic reconstructions of human brain regions, I want to study the metabolic signatures associated with ATNC markers. In my previous study with the ADMC consortium, we studied the sphingolipid pathway and identified S1P receptor that can be modulated to improve cognition (https://www.medrxiv.org/content/10.1101/2021.07.16.21260601v1). I want to study amino acid metabolism and bioenergetics in AD individuals using a similar approach.
Additional Investigators