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Principal Investigator  
Principal Investigator's Name: ADEM ALBAYRAK
Institution: Alzheon
Department: Operations
Country:
Proposed Analysis: We seek to analyze the longitudinal change/decline in episodic memory (i.e. RAVLT clinical memory test) in MCI and mild AD patients stratified by APOE4 genotype. We also plan to evaluate impact of factors such as demographics or baseline biomarkers and their role in how they might affect clinical progression. These data are expected to yield valuable clinical information that will help the understanding of how changes in episodic memory progresses over time based on APOE4 status and will be used to guide future clinical AD efficacy trials that employ this clinical memory test. It is expected that the results from this analysis will published in leading peer reviewed clinical AD journals and/or clinical AD conferences.
Additional Investigators  
Investigator's Name: John Hey
Proposed Analysis: We seek to analyze the longitudinal change/decline in episodic memory (i.e. RAVLT clinical memory test) in MCI and mild AD patients stratified by APOE4 genotype. We also plan to evaluate impact of factors such as demographics or baseline biomarkers and their role in how they might affect clinical progression. These data are expected to yield valuable clinical information that will help the understanding of how changes in episodic memory progresses over time based on APOE4 status and will be used to guide future clinical AD efficacy trials that employ this clinical memory test. It is expected that the results from this analysis will be published in leading peer reviewed clinical AD journals and/or clinical AD conferences.
Investigator's Name: Daniel Lancour
Proposed Analysis: We seek to analyze the longitudinal change/decline in episodic memory (i.e. RAVLT clinical memory test) in MCI and mild AD patients stratified by APOE4 genotype. We also plan to evaluate impact of factors such as demographics or baseline biomarkers and their role in how they might affect clinical progression. These data are expected to yield valuable clinical information that will help the understanding of how changes in episodic memory progresses over time based on APOE4 status and will be used to guide future clinical AD efficacy trials that employ this clinical memory test. It is expected that the results from this analysis will be published in leading peer reviewed clinical AD journals and/or clinical AD conferences.
Investigator's Name: Erwan de Naurois
Proposed Analysis: RWD analysis of patient progression