×
  • Select the area you would like to search.
  • ACTIVE INVESTIGATIONS Search for current projects using the investigator's name, institution, or keywords.
  • EXPERTS KNOWLEDGE BASE Enter keywords to search a list of questions and answers received and processed by the ADNI team.
  • ADNI PDFS Search any ADNI publication pdf by author, keyword, or PMID. Use an asterisk only to view all pdfs.

Question

Question Posted 10/29/14:
How do neurons die in Alzheimer's disease? What is the mechanism of cell death?
Response posted 10/29/14 by michael weiner:
This is a complicated question, which is beyond the scope of ADNI, a clinical study. In brief, Alzheimer's disease is charachterized by the accumulation of two proteins: beta amyloid and tau. The accumulation of tau tangles is associated with neurodegeneration. The specific mechanisms of cell death are being investigated in animal models
Go back to list of topics >