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ACCESS DATA AND SAMPLES

Learn about ADNI Data

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Access Data

All ADNI data are shared without embargo through the LONI Image and Data Archive (IDA), a secure research data repository. Interested scientists may obtain access to ADNI imaging, clinical, genomic, and biomarker data for the purposes of scientific investigation, teaching, or planning clinical research studies. Access is contingent on adherence to the ADNI Data Use Agreement and the publications’ policies outlined in the documents listed below. Note: documents are subject to updates by ADNI.

Data from several dementia studies complementary to ADNI are also available through the IDA. These include the DoD-ADNI study, which measures the effects of traumatic brain injury and post-traumatic stress disorder on Alzheimer’s disease in veterans, and the AIBL study (Australian Imaging Biomarkers and Lifestyle Study of Aging). More information about DoD-ADNI and AIBL may be found on the Collaborative Studies page.

APPLY FOR ACCESS TO DATA

The application process includes acceptance of the Data Use Agreement and submission of an online application form. The application must include the investigator’s institutional affiliation and the proposed uses of the ADNI data. ADNI data may not be used for commercial products or redistributed in any way.

Click on the buttons below to apply for ADNI data, DoD-ADNI data, AIBL data, or all three.

Note: Each study has its own Data Use Agreement. Obtaining access to and using ADNI data requires adherence to the ADNI Data Use Agreement and the publication policies outlined in the documents listed above and in the links below. Documents are subject to updates by ADNI.
Application Review

The ADNI Data Sharing and Publications Committee (DPC) generally reviews data use applications within one week of submission. Each application is carefully reviewed to verify investigator affiliation with a scientific or educational institution and on the basis of the proposed research or data use. Incomplete applications or those without a clear focus will not receive approval. The results of the Committee’s review will be sent via email. Approved applicants will receive login information to access and download ADNI data from the LONI Image and Data Archive (IDA).

MAINTAINING YOUR ADNI DATA USE ACCOUNT

A provision of the ADNI Data Use Agreement requires submission of an annual update. Accounts will automatically expire if no update is submitted within the allotted time. You will receive an email reminding you that your annual update is due approximately one month before your account expires. You may also add or remove co-investigators, submit manuscripts and update contact information at that time or at any time in advance. Login to update your account information.

QUESTIONS ABOUT YOUR ACCOUNT

If you have questions about using your ADNI data account, please review the User Account Frequently Asked Questions or contact us.

Access Samples

Biospecimens such as blood, urine, brain tissue and cerebrospinal fluid collected from ADNI participants are available through ADNI and managed by the Resource Allocation Review Committee (RARC). Any scientist may apply for biomarker samples collected by ADNI. To fully understand the number of subjects and sample collection, refer to the ADNI Protocol and Biofluids section of the ADNI procedures manual.

Brain tissue may be requested through the Resource Allocation Review Committee (RARC). Please see details for application below and refer any questions to tmontine@stanford.edu.

Please Note: Following application approval by the RARC, samples will be provided to investigators with coded identifiers. Per ADNI policy, all results must be submitted to the ADNI representative when analysis and quality control are completed, at which time they will be re-linked and uploaded into the ADNI database where you (and others) may access them. Use of ADNI samples for technology development or comparisons among different technologies is not recommended for well-established analytes unless there is preliminary data showing clearly superior performance.

APPLY FOR ACCESS TO SAMPLES

Applications will follow the format of NIH R01 limited to 5 pages. Only manuscripts accepted for publication, published manuscripts, and submitted grants will be considered as appendix material.

Detailed information on the NIH R01 can be found here. Include sections on Hypothesis and Specific Aims, Background and Significance, Preliminary Studies, and Experimental Plan. Please limit to 5 pages, and follow NIH guidelines for a R01 application.

Questions and completed applications should be sent to the Resource Allocation Review Committee (RARC) at tmontine@stanford.edu.