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Principal Investigator  
Principal Investigator's Name: Li Shen
Institution: University of Pennsylvania
Department: Biostatistics, Epidemiology and Informatics
Country:
Proposed Analysis: In general, our group is interested in developing computational and informatics methods for integrative analysis of multimodal imaging data, high throughput "omics" data, cognitive and other biomarker data, with applications to various complex disorders including Alzheimer’s disease. We will use the ADNI data as a test bed to achieve the following two goals: (1) advance computer science and bioinformatics by producing novel algorithms for analyzing large scale heterogeneous data sets; and (2) provide important new insights into the phenotypic characteristics and genetic mechanisms of normal and/or disordered biological structures and functions to impact the development of new diagnostic, therapeutic and preventive approaches.
Additional Investigators  
Investigator's Name: Brian Lee
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Jeffrey Qu
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Jingxuan Bao
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Jin Chong
Proposed Analysis: Develop and implement computational and statistical methods for analyzing multimodal imaging, genomics, biomarker, cognitive and clinical data.
Investigator's Name: Zixuan Wen
Proposed Analysis: Develop and implement computational and statistical methods for analyzing multimodal imaging, genomics, biomarker, cognitive and clinical data.
Investigator's Name: Sumita Garai
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Shu Yang
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Jin-seo Kim
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Daniele Pala
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Mary Regina Boland
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Aditya Kashyap
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Boning Tong
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Frederick Xu
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Shizhuo Mu
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Zexuan Wang
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Bojian Hou
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Ruiming Wu
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.
Investigator's Name: Manu Shivakumar
Proposed Analysis: Develop and implement computational methods for analyzing multimodal imaging data, and relating those to other biomarker, clinical and cognitive data.