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Principal Investigator  
Principal Investigator's Name: Jeannie-Marie Leoutsakos
Institution: Johns Hopkins School of Medicine
Department: Psychiatry
Country:
Proposed Analysis: I am planning to do some simulations to determine power for a clinical trial in MCI (primary analysis will be a mixed effects model for comparison of rates of decline between treated and untreated). I want to use the ADNI data to identify realistic parameter values for the mixed effects model, including rate and shape of decline, variance-covariance matrix of random effects, and patterns and rates of missingness.
Additional Investigators