There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Matthew Panizzon |
| Institution: | University of California San Diego |
| Department: | Psychiatry |
| Country: | |
| Proposed Analysis: | Decline in the primary male androgen testosterone has been shown to be a risk factor for the development of mild cognitive impairment and Alzheimer's disease. To date, the mechanisms by which this association occur remain poorly understood. We will examine the association between testosterone levels and biological markers of Alzheimer's pathology (CSF and plasma based measures of Amyloid and Tau) and indicators of more generalized neuropathology (neurofilament light) in order to elucidate these potential mechanisms, their impact on cognition, and progression from normal cognitive functioning to MCI and dementia. |
| Additional Investigators |
