There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Haitao Yang |
| Institution: | Hebei Medical University |
| Department: | Epidemeology and health statistics |
| Country: | |
| Proposed Analysis: | We are tying to develope a multivariate regression model to detect the genes associated with Alzheimer's Disease.The SNPs information will serve as the predictor and further be mapped to genes. We will infer genetic effects at the gene level (group level) not individual SNP level.In the future,we are going to introduce the kernel method to the multivariate regression for capturing the underlying nonlinear relationships between genes and imaging response of Alzheimer's Disease. |
| Additional Investigators | |
| Investigator's Name: | Jing Yuan |
| Proposed Analysis: | In order to boost the power of detecting the genes, we will jointly use the p-values combination methods and omnibus test to adapt different genetic effects assumption.The model based on omnibus test will be a powerful and robust statistical inference tool. |
| Investigator's Name: | Xin Wang |
| Proposed Analysis: | I am going to use the group-wised envelope method to improve the power of regression analysis based on the imaging data, especially for the small sample size. |
| Investigator's Name: | Xin Wang |
| Proposed Analysis: | I am going to use the group-wised envelope method to improve the power of regression analysis based on the imaging data, especially for the small sample size. |
| Investigator's Name: | Xin Wang |
| Proposed Analysis: | I am going to use the group-wised envelope method to improve the power of regression analysis based on the imaging data, especially for the small sample size. |
