×
  • Select the area you would like to search.
  • ACTIVE INVESTIGATIONS Search for current projects using the investigator's name, institution, or keywords.
  • EXPERTS KNOWLEDGE BASE Enter keywords to search a list of questions and answers received and processed by the ADNI team.
  • ADNI PDFS Search any ADNI publication pdf by author, keyword, or PMID. Use an asterisk only to view all pdfs.
Principal Investigator  
Principal Investigator's Name: Lana Garmire
Institution: University of Michigan
Department: Department of Computational Medicine and Bioinform
Country:
Proposed Analysis: We plan to do some classification or prognosis prediction based on Alzheimer's metabolomics, genetics/genomics and clinical datasets using R package Lilikoi v2. This project would first transform the metabolite/gene names to the HMDB ids and computes the pathway deregulation score for a given set of metabolites/genes. Then we will select the pathways with the highest significance and do classification based on these selected pathways. We will apply and compare multiple machine learning methods such as Random Forest, SVM, LDA and neural network. If the patient prognosis information is available, we plan to perform prognosis prediction too.
Additional Investigators  
Investigator's Name: Gaurav Shetty
Proposed Analysis: genomics, metabolomics and imaging analysis
Investigator's Name: Entong Li
Proposed Analysis: metabolomics analysis