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Principal Investigator  
Principal Investigator's Name: Yikuan Li
Institution: Northwestern University
Department: Preventive Medicine
Country:
Proposed Analysis: Heterogeneous data, including genetics, image data, clinical variables, are all essential to predict Alzheimer's disease. Learning the multimodal representation from multiple data formats is the bedrock for the predictive models. Current research in this area usually modals different data sources separately and add merging function to integrate them together. However, this genre of methods ignore the interaction of datasets. Our preliminary research on thoracic disorder identification shows that the joint learning strategy using transformer-based model can significant improve the performance of multimodal representation learning. We would like to transfer our success to the prediction of AD.
Additional Investigators  
Investigator's Name: Hanyin Wang
Proposed Analysis: Heterogeneous data, including genetics, image data, clinical variables, are all essential to predict Alzheimer's disease. Learning the multimodal representation from multiple data formats is the bedrock for the predictive models. Current research in this area usually modals different data sources separately and add merging function to integrate them together. However, this genre of methods ignore the interaction of datasets. Our preliminary research on thoracic disorder identification shows that the joint learning strategy using transformer-based model can significant improve the performance of multimodal representation learning. We would like to transfer our success to the prediction of AD. I am the co-author of the main applicant.