There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Huanyao Gao |
Institution: | Mayo Clinic |
Department: | Molecular Pharmacology & Experimental Therapeutics |
Country: | |
Proposed Analysis: | Mayo Clinic team Profs. Trushina and Wang are going to collaborate with Prof. Rima Kaddurah-Daouk and the Alzheimer’s Disease Metabolomics Consortium on this project aiming to identify potentially targetable pathways related to mitochondria metabolism and homeostasis in Alzheimer's disease. Specific aims include: 1. Identify appropriate transcriptomic, proteomic, metabolomic markers associated with bioenergetic deficiency/mitochondria dysfunction 2. Identify appropriate covariates for patient stratification, and 3. Discover drugs targeting these markers in different population |
Additional Investigators | |
Investigator's Name: | Eugenia Trushina |
Proposed Analysis: | Mayo Clinic team Profs. Trushina and Wang are collaborating with Prof.Rima Kaddurah-Daouk and the Alzheimer’s Disease Metabolomics Consortium on this project aiming to identify potentially targetable pathways related to mitochondria metabolism and homeostasis in Alzheimer's disease. Specific aims include: 1. Identify appropriate transcriptomic, proteomic, metabolomic markers associated with bioenergetic deficiency/mitochondria dysfunction 2. Identify appropriate covariates for patient stratification, and 3. Discover drugs targeting these markers in different population. |
Investigator's Name: | Liewei Wang |
Proposed Analysis: | Mayo Clinic team Profs. Trushina and Wang are collaborating with Prof.Rima Kaddurah-Daouk and the Alzheimer’s Disease Metabolomics Consortium on this project aiming to identify potentially targetable pathways related to mitochondria metabolism and homeostasis in Alzheimer's disease. Specific aims include: 1. Identify appropriate transcriptomic, proteomic, metabolomic markers associated with bioenergetic deficiency/mitochondria dysfunction 2. Identify appropriate covariates for patient stratification, and 3. Discover drugs targeting these markers in different population. |