There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Neelroop Parikshak |
| Institution: | Regeneron Pharmaceuticals Inc. |
| Department: | Regeneron Genetics Center |
| Country: | |
| Proposed Analysis: | We propose to utilize ADNI data to define structural imaging correlates of Alzheimer's disease state and progression. We will do this by applying models to predict disease state, as defined by clinical status, cognitive tests, or biomarkers, with structural imaging data. We will then use the structural imaging correlates of disease defined in ADNI in other datasets to define participant risk for Alzheimer's. We will may also use ADNI data in meta-analyses of Alzheimer's disease risk and/or progression in genetic studies related to neurodegeneration. |
| Additional Investigators | |
| Investigator's Name: | Giovani Coppola |
| Proposed Analysis: | I will be coordinating some of the analyses discussed by Dr. Parikshak. |
| Investigator's Name: | Jose Bras |
| Proposed Analysis: | Investigation of polygenic risk scores and rare variants using longitudinal ADNi data. Integration with findings in datasets derived from the Regeneron Genetics Center. |
| Investigator's Name: | Sean Yu |
| Proposed Analysis: | Standardization of clinical data from ADNI. |
| Investigator's Name: | Deepika Sharma |
| Proposed Analysis: | Standardization of clinical phenotypes. |
