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Principal Investigator  
Principal Investigator's Name: Jeremiah Ronquillo
Institution: Geronimo Ronquillo LLC
Department: Biomedical Informatics
Country:
Proposed Analysis: The ability to detect Alzheimer’s disease earlier in its course would give patients, their families, and physicians a better opportunity to prepare for, treat, and manage this condition. Different genetic, clinical, laboratory, and imaging modalities have shown progress in being able to identify or predict individuals at increased risk for Alzheimer’s disease, although no single modality has been shown to be effective for all situations. The recent push towards increased Electronic Health Record (EHR) use in hospitals and clinics provides an opportunity to leverage the strengths of existing approaches to more accurately assess Alzheimer’s disease in patients. Most EHRs provide a centralized location to store all aspects of medical data accumulated over a patient’s lifetime. The combined analysis of different modalities could provide earlier and more comprehensive insight into patient risk for Alzheimer’s disease than any single approach could. The goal for this study is to analyze demographic, clinical, laboratory, imaging, and genetic data from this database in a way similarly represented in EHRs in order to understand the combination of modalities that could give the best assessment of a patient’s risk for Alzheimer’s disease.
Additional Investigators