There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Maciej Plocharski |
| Institution: | Aalborg University |
| Department: | Health Science and Technology |
| Country: | |
| Proposed Analysis: | I am applying for access to ADNI data, which I will use during my PhD at the Department of Health Science and Technology at Aalborg University, Aalborg, Denmark. The aim of my PhD project is to improve the quality of diagnosis and prognosis of neurological disorders such as Alzheimer’s disease by exploring sulcal morphology of human brain data. The focus is on successful application of biomarkers in sulcal morphology of the brain to monitor changes in the state of the sulci as a progression indication of Alzheimer’s disease. It is believed that many cortical sulci are linked to the underlying cytoarchitectonic and functional organization of the brain. Hence, shape analysis of the sulci can prove useful for studying developmental disorders, normal brain maturation and ageing. This project will therefore focus on how the sulcal structure correlates with the progression of Mild Cognitive Impairment and Alzheimer’s disease. The PhD project is planned to consist of three studies. The first study involves using statistical sulcal morphology to investigate methods to identify, extract, and analyze sulci from magnetic resonance images of human brain. The aim of the second study is to create an atlas-based approach utilizing sulcal morphology for detecting AD. The third study will investigate the applicability of cortical thickness measurement and sulcal morphology as possible biomarkers for AD. |
| Additional Investigators |
