There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Yacila Deza Araujo |
Institution: | University of the Bundeswehr |
Department: | Psychology |
Country: | |
Proposed Analysis: | CRP and ApoE$ have detrimental effects for cognition, but in different manner. On one hand, ApoE$ is related to late onset of ALzheime'rs disease and also impact cognition at younger ages. On the other hand, CRP is related to imflammation and also, associated with lower cognition. However, carriers of the ApoE4 - a well-know risk factor for AD - have lower CRP levels. A recent hypothesis proposed a regulatory mechanism of lifetime stress responses in ApoE4 carriers that would contribute to decreases in CRP levels. Our aim is to disentangle the role of CRP-ApoE4 in cognition using several datasets and, later, investigating brain markers shared by both high CPR levesl and the ApoE4 allele |
Additional Investigators | |
Investigator's Name: | Anna Rieckmann |
Proposed Analysis: | Professor of the chair of Biological Psychology supervising the project. |