There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Timo Oberstein |
Institution: | Friedrich-Alexander University |
Department: | Department of Psychiatry and Psychotherapy |
Country: | |
Proposed Analysis: | In the present study, we would like to identify differences between mild cognitive impairment (MCI) with Tau (Tau+) and amyloid pathology (Ab+) as assessed with CSF biomarkers, MCI Tau+ Ab-, and MCI Tau- and Ab+. Each participant was/will be assessed with the german version of the CERAD neuropsychological battery (CERAD NB+), with MRI of the head including MP RAGE sequence, with CSF diagnostics and with inflammatory plasma biomarkers. Based on the MRI data, a VBM and SBM analysis should be performed and compared with items of the CERAD-NP+ as well as with levels of the other biomarkers. In order to perform a proper sample size calculation, we would like to perform the VBM and SBM Analysis with ADNI data in advance. |
Additional Investigators | |
Investigator's Name: | Haas Anna-Lena |
Proposed Analysis: | VBM and SBM of MCI possibly due to AD, i.e. Tau+Ab- and Tau-Ab+, and MCI probably due to AD |