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Principal Investigator  
Principal Investigator's Name: Denis Smirnov
Institution: UC San Diego
Department: Neuroscience Graduate Program / Neurosciences
Country:
Proposed Analysis: We are interested in using ADNI as a confirmation dataset for our project looking at the interaction of csf biomarkers (AB40, AB42, Tau, p-Tau, NPTX2, SNAP25, Neurogranin, and NfL) at the UCSD ADRC. We would like to use the most recent csf assays available in ADNI to examine the interaction of these csf biomarkers in relation to each other, and attempt to determine if some are redundant or have added value in predicting diagnosis, functional and cognitive status, and progression.
Additional Investigators  
Investigator's Name: James Brewer
Proposed Analysis: PhD Mentor of Denis Smirnov
Investigator's Name: Douglas Galasko
Proposed Analysis: CSF Biomarker expert for analyses of local and ADNI data